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Nuclear Medicine Applications

Scope of Nuclear Medicine Imaging

Diagnostic Imaging

Letting the Body Speak: Precision Lesion Visualization

By introducing radiopharmaceuticals into the body, human tissues emit "endogenous radiation." Highly sensitive detection equipment captures these radiation signals to accurately map lesion distribution based on tissue uptake and attenuation properties, providing cellular-level insights beyond the reach of conventional anatomical imaging.

Targeted Radionuclide Therapy

Micro-Scale Precision: Targeted Eradication of Cancer Cells

Once target sites are identified, therapeutic radiopharmaceuticals deliver micro-scale energy directly into tumors. High-energy particles released during radioactive decay (α or β particles) focus precisely on diseased tissue, generating potent ionization effects that shatter cancer cell DNA while minimizing collateral damage to surrounding healthy tissue.

Precision Medicine / Theranostics Theranostics

See What You Treat, Treat What You See

Theranostics utilizes diagnostic imaging to stratify eligible patients, followed by targeted radionuclide therapy using matching molecular ligands. This approach not only enhances therapeutic efficacy but also significantly reduces the systemic side effects of conventional treatments, ushering in a new era of precision oncology—a core focus of Petpharmbio's strategic R&D roadmap.

▲ Therapeutic Radiopharmaceuticals Fall into Two Primary Classes:

α-Emitting Radionuclides — Emit alpha particles with high linear energy transfer (LET) but an extremely short path length (<100 μm, cell-diameter scale), ideal for treating micro-metastases. Representative Isopes: 225Ac, 211At

β-Emitting Radionuclides — Emit beta particles with longer tissue penetration range and lower LET compared to alpha particles, suited for local tumor control. Representative Isotopes: 177Lu, 161Tb

Therapeutic Radiopharmaceutical R&D

β Decay (Beta Decay)

Moderate energy with millimeter-range tissue penetration (0.5 MeV / ~1 mm), providing effective localized tumor control.
Key Radionuclides: 177Lu, 131I

α Decay (Alpha Decay)

High cytotoxicity with cellular-scale range (<100 μm), delivering maximal localized cell killing with minimal off-target exposure.
Key Radionuclides: 225Ac, 211At

Targeted therapeutic radiopharmaceuticals represent the core focus of Petpharmbio's ongoing research and development initiatives.